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pure autonomic failure

MeSH: D054970ORPHA: 441

Contents

  1. 1. Overview
  2. 2. Available Treatments
  3. 3. Clinical Presentation
  4. 4. Classification & Codes

Overview

neurodegenerative disease that affects the sympathetic branch of the autonomous nervous system and that manifests with orthostatic hypotension

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with pure autonomic failure, sourced from HPO and Orphanet clinical annotations.

AnhidrosisOrthostatic hypotensionAbnormality of circulating catecholamine levelAbnormal autonomic nervous system physiologyConstitutional symptomUrinary incontinenceSyncopeConstipationDysuriaImpotence

Classification & Codes

MeSH Code

D054970

Orphanet Code

ORPHA:441
pure autonomic failure
MeSHD054970
OrphanetORPHA:441
Treatments0 drug(s)
Symptoms on record10 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO