Rabson–Mendenhall syndrome

ICD-10: E13ORPHA: 769

Overview

medical condition

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Rabson–Mendenhall syndrome, sourced from HPO and Orphanet clinical annotations.

Reduced subcutaneous adipose tissueShort statureFasting hyperinsulinemiaClitoral hypertrophySevere postnatal growth retardationPostprandial hyperglycemiaOnychauxisHypertrichosisHirsutismIntellectual disabilityGlobal developmental delayIntrauterine growth retardationRecurrent infectionsFasting hypoglycemiaLong penisAbnormality of the dentitionDental crowdingInsulin-resistant diabetes mellitusInsulin resistanceAcanthosis nigricansDry skinIncreased serum testosterone levelIncreased circulating androgen concentrationIncreased C-peptide levelLichenoid skin lesionThick hairEnlarged ovariesNephrocalcinosisMacroglossiaGingival overgrowthHigh palateFurrowed tongueCoarse facial featuresLow anterior hairlineMandibular prognathiaMacrotiaProminent nasal bridgeWide noseAnteverted naresRetinopathyHypothyroidismPrecocious pubertyVentricular septal defectAtrial septal defectCardiomyopathyDiabetic ketoacidosisPolydipsiaPremature graying of hairDelayed skeletal maturationHypokalemiaAdvanced eruption of teethCNS demyelinationPeripheral neuropathyPolydactylyIncreased pineal volumeImpaired glucose tolerance

Classification & Codes

ICD-10 Code

E13

Orphanet Code

ORPHA:769
Rabson–Mendenhall syndrome
ICD-10E13
OrphanetORPHA:769
Treatments0 drug(s)
Symptoms on record56 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO