Rasmussen's encephalitis

ICD-10: G04.8MeSH: C535291ORPHA: 79138

Overview

rare inflammatory neurological disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Rasmussen's encephalitis, sourced from HPO and Orphanet clinical annotations.

OphthalmoplegiaAtaxiaConfusionDrowsinessEMG: decremental response of compound muscle action potential to repetitive nerve stimulationDecreased motor nerve conduction velocityCNS demyelinationSevere infectionDiplopiaAreflexiaPneumoniaDyspneaAbnormality of the autonomic nervous systemEEG abnormalityIncreased CSF protein concentrationLimb muscle weaknessAcute demyelinating polyneuropathyFacial paralysisAbnormal pyramidal signRespiratory tract infectionDysesthesiaAbnormal thalamic MRI signal intensityAutoimmune antibody positivityAbnormality of eye movementPtosisNystagmusComaBulbar palsyAbnormal cranial nerve morphologyReduced tendon reflexesBrisk reflexesTetraparesisTetraplegiaRespiratory failureBabinski signRespiratory failure requiring assisted ventilationAnisocoriaFacial palsyImpaired proprioceptionSensory ataxiaMydriasisCSF pleocytosisHypercapniaPainWeakness of facial musculatureRecurrent gastroenteritisExcessive daytime somnolenceInflammation

Classification & Codes

ICD-10 Code

G04.8

MeSH Code

C535291

Orphanet Code

ORPHA:79138
Rasmussen's encephalitis
ICD-10G04.8
MeSHC535291
OrphanetORPHA:79138
Treatments0 drug(s)
Symptoms on record48 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO