retinitis pigmentosa-deafness syndrome

ORPHA: 231183

Overview

Usher syndrome characterized by retinitis pigmentosa and onset of sensorineural hearing impairment in the teens that has material basis in mutation in the MTTS2 gene in the mitochondrial genome

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with retinitis pigmentosa-deafness syndrome, sourced from HPO and Orphanet clinical annotations.

Abnormal vestibular functionAbnormal cochlea morphologySensorineural hearing impairmentRod-cone dystrophyAbnormal electroretinogramVisual lossScotomaNyctalopiaVestibular hyporeflexiaIris hypopigmentationDepressionAnxiety

Classification & Codes

Orphanet Code

ORPHA:231183
retinitis pigmentosa-deafness syndrome
OrphanetORPHA:231183
Treatments0 drug(s)
Symptoms on record12 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO