rheumatoid factor-negative juvenile idiopathic arthritis

ORPHA: 854081 Treatment Available

Overview

human disease

Available Treatments (1)

DrugFormStatusCountriesLead Time
Tofacitinib
Oral tabletFDA Approved5

Clinical Presentation

Signs and symptoms associated with rheumatoid factor-negative juvenile idiopathic arthritis, sourced from HPO and Orphanet clinical annotations.

ArthritisJoint swellingJoint stiffnessAnkle swellingArthralgiaAbnormality of the wristElevated erythrocyte sedimentation rateKnee osteoarthritisSynovial lining hyperplasiaEnthesitisSynovitisUveitisAbnormality of the handFlexion contractureAbnormal hip joint morphologyMild postnatal growth retardationWeight lossAbnormal metatarsal morphologyAnemiaLymphadenopathyAbnormal shoulder morphologyAbnormality of the cervical spineMyalgiaAntinuclear antibody positivityHip osteoarthritisAbnormality of the temporomandibular jointLow-grade feverAbnormal metacarpophalangeal joint morphologyOligoarthritisIridocyclitisHepatosplenomegaly

Classification & Codes

Orphanet Code

ORPHA:85408
rheumatoid factor-negative juvenile idiopathic arthritis
OrphanetORPHA:85408
Treatments1 drug(s)
Symptoms on record31 signs
Statuspublished

Treatment Summary

Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO