rheumatoid factor-positive polyarticular juvenile idiopathic arthritis

ORPHA: 85435

Overview

category of juvenile idiopathic arthritis defined by the presence of arthritis affecting five or more separate joints during the first six months of disease, with positive serologic testing for rheumatoid factor

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with rheumatoid factor-positive polyarticular juvenile idiopathic arthritis, sourced from HPO and Orphanet clinical annotations.

Abnormal circulating interleukin concentrationArthritisArthralgiaRheumatoid factor positivePolyarticular arthritisLimitation of joint mobilityJoint swellingAbnormal limb bone morphologyElevated erythrocyte sedimentation rateProgressive joint destructionAbnormal epiphysis morphologyInterphalangeal joint erosionsElevated circulating C-reactive protein concentrationSymmetric polyarthritisSynovitisOsteopeniaReduced bone mineral densityPremature epimetaphyseal fusionAsymmetric growth

Classification & Codes

Orphanet Code

ORPHA:85435
rheumatoid factor-positive polyarticular juvenile idiopathic arthritis
OrphanetORPHA:85435
Treatments0 drug(s)
Symptoms on record19 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO