rickets

MeSH: D012279ORPHA: 289157

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with rickets, sourced from HPO and Orphanet clinical annotations.

RicketsHypocalcemiaLow serum calcitriolSecondary hyperparathyroidismDeformed rib cageRachitic rosaryEnlargement of the costochondral junctionMotor delayTetanyMuscle weaknessFailure to thriveHypophosphatemiaBone painIncreased susceptibility to fracturesDelayed epiphyseal ossificationOsteomalaciaSparse bone trabeculaeThin bony cortexGeneralized aminoaciduriaGenu varumFemoral bowingTibial bowingEnlargement of the wristsEnlargement of the anklesSubperiosteal bone resorptionElevated circulating parathyroid hormone levelIrregular, rachitic-like metaphysesFlat occiputPostnatal growth retardationWide cranial suturesElevated alkaline phosphatase of bone originGait disturbanceGeneralized hypotoniaCardiomyopathyHypochromic anemiaFrontal bossingElevated circulating alkaline phosphatase concentrationShort statureDelayed eruption of teethIrritabilityProtuberant abdomenSplenomegalyIncreased total leukocyte countHypocalcemic seizuresHepatomegalyEnamel hypoplasia

Classification & Codes

MeSH Code

D012279

Orphanet Code

ORPHA:289157
rickets
MeSHD012279
OrphanetORPHA:289157
Treatments0 drug(s)
Symptoms on record46 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO