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Riley-Day syndrome

MeSH: D004402ORPHA: 1764

Contents

  1. 1. Overview
  2. 2. Available Treatments
  3. 3. Clinical Presentation
  4. 4. Classification & Codes

Overview

hereditary sensory and autonomic neuropathy type III (HSAN-III), is a disorder of the autonomic nervous system which affects the development and survival of sensory

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Riley-Day syndrome, sourced from HPO and Orphanet clinical annotations.

Abnormality of the kidneyRenal insufficiencyAlacrimaMyopiaAbnormal pupil morphologyOptic atrophyAtypical behaviorHypertensionHypohidrosisHyperhidrosisAcrocyanosisHeterochromia iridisSeizureAtaxiaHypotoniaHyporeflexiaOrthostatic hypotensionGait disturbanceGrowth delayTachycardiaGastroesophageal refluxMalignant hyperthermiaAbnormal pleura morphologyRecurrent respiratory infectionsAbnormal peritoneum morphologyScoliosisRecurrent fracturesOsteolysisHyponatremiaEMG abnormalityImpaired pain sensationCorneal opacityFeeding difficulties in infancyPeripheral neuropathyAvascular necrosisGlomerulopathyCorneal erosion

Classification & Codes

MeSH Code

D004402

Orphanet Code

ORPHA:1764
Riley-Day syndrome
MeSHD004402
OrphanetORPHA:1764
Treatments0 drug(s)
Symptoms on record37 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO