RIN2 syndrome

MeSH: C567770ORPHA: 217335

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with RIN2 syndrome, sourced from HPO and Orphanet clinical annotations.

Abnormal lip morphologyGingival overgrowthHigh palateCoarse facial featuresLong philtrumDownslanted palpebral fissuresHyperextensible skinHirsutismJoint hypermobilityRedundant skinPes planusSparse scalp hairScoliosisInfra-orbital foldUpper eyelid edemaIrregular dentitionAbnormal sternum morphologyBruising susceptibilityUmbilical herniaAbnormally high-pitched voiceCognitive impairmentCryptorchidismHypergonadotropic hypogonadismBrachydactylyIncreased susceptibility to fracturesAortic aneurysmPremature ovarian insufficiencyHigh myopia

Classification & Codes

MeSH Code

C567770

Orphanet Code

ORPHA:217335
RIN2 syndrome
MeSHC567770
OrphanetORPHA:217335
Treatments0 drug(s)
Symptoms on record28 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO