ring chromosome 22

MeSH: C536795ORPHA: 1446

Overview

rare chromosomal disorder

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with ring chromosome 22, sourced from HPO and Orphanet clinical annotations.

AzoospermiaMicrocephalyDolichocephalyLong faceEpicanthusFull cheeksPointed chinMacrotiaBulbous noseThick eyebrowInappropriate behaviorAutistic behaviorDelayed speech and language developmentEdemaLymphedemaNeurofibromaLarge handsSeizureGlobal developmental delayGeneralized hypotoniaGrowth delayGait ataxiaDevelopmental regression2-3 toe syndactylyImpaired pain sensationProtruding tongueMidface retrusionThick vermilion borderWide nasal baseToenail dysplasiaAgenesis of corpus callosumAbsent septum pellucidumPleural effusion

Classification & Codes

MeSH Code

C536795

Orphanet Code

ORPHA:1446
ring chromosome 22
MeSHC536795
OrphanetORPHA:1446
Treatments0 drug(s)
Symptoms on record33 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO