SAPHO syndrome
MeSH: D020083ORPHA: 793
Overview
variety of inflammatory bone disorders that may be associated with skin changes
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with SAPHO syndrome, sourced from HPO and Orphanet clinical annotations.
Abnormal thorax morphologyAbnormality of the vertebral columnEdemaSkin rashAcneArthritisRecurrent skin infectionsMalabsorptionAbdominal painChronic diarrheaInflammation of the large intestineSteatorrheaBone painOsteomyelitisRecurrent fracturesOsteolysisArthralgiaPsoriasiform dermatitisVenous thrombosisCraniofacial osteosclerosisCranial nerve paralysisNeoplasm of the skeletal systemEnthesitisSynovitisAbnormal sacroiliac joint morphologyPalmoplantar pustulosisPustuleVasculitisChest painHyperostosis
Classification & Codes
MeSH Code
D020083Orphanet Code
ORPHA:793SAPHO syndrome
| MeSH | D020083 |
| Orphanet | ORPHA:793 |
| Treatments | 0 drug(s) |
| Symptoms on record | 30 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO