Scheie syndrome

ORPHA: 93474

Overview

mucopolysaccharidosis characterized by corneal clouding, facial dysmorphism and normal lifespan

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Scheie syndrome, sourced from HPO and Orphanet clinical annotations.

Wide mouthEverted lower lip vermilionCoarse facial featuresSensorineural hearing impairmentGlaucomaAbnormality of the skeletal systemLimitation of joint mobilityJoint stiffnessAortic regurgitationSplenomegalyHepatomegalySpastic paraparesisCorneal opacityMucopolysacchariduriaRhinitisThick vermilion borderAbnormal nerve conduction velocityCerebral palsy

Classification & Codes

Orphanet Code

ORPHA:93474
Scheie syndrome
OrphanetORPHA:93474
Treatments0 drug(s)
Symptoms on record18 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO