Schimmelpenning syndrome

ICD-10: Q85.8MeSH: D054000ORPHA: 3205

Overview

neurocutaneous syndrome with anomalies of the central nervous system, ocular system, skeletal system, cardiovascular system, and genitourinary system. A triad of sebaceous nevi, seizures, and mental retardation

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Schimmelpenning syndrome, sourced from HPO and Orphanet clinical annotations.

HyperostosisOcular painFacial capillary hemangiomaSeizureCapillary hemangiomaStrabismusGlaucomaOptic atrophyAtypical behaviorDelayed speech and language developmentVisual field defectIntellectual disabilityStrokeHyperreflexiaHeadacheAttention deficit hyperactivity disorderLens luxationArachnoid hemangiomatosisInfantile spasmsNeurodevelopmental delayAbnormal cerebral vascular morphologyGingival overgrowthHydrocephalusMacrocephalyHearing abnormalityAbnormality of visionConjunctival telangiectasiaRetinal detachmentBuphthalmosVisual lossAbnormal choroid morphologyIris colobomaBlindnessDental malocclusionAutistic behaviorHeterochromia iridisCorneal dystrophyDysphagiaCerebral cortical atrophyPulmonary embolismChiari malformationSleep disturbanceCerebral calcificationVenous thrombosisChoroidal hemangiomaAbnormal retinal vascular morphologyEpiphoraCentral hypothyroidismHemianopiaReduced circulating growth hormone concentrationVisceral angiomatosis

Classification & Codes

ICD-10 Code

Q85.8

MeSH Code

D054000

Orphanet Code

ORPHA:3205
Schimmelpenning syndrome
ICD-10Q85.8
MeSHD054000
OrphanetORPHA:3205
Treatments0 drug(s)
Symptoms on record51 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO