Seckel syndrome 7

ORPHA: 319675

Overview

Seckel syndrome that has material basis in compound heterozygous mutation in the NIN gene on chromosome 14q22

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Seckel syndrome 7, sourced from HPO and Orphanet clinical annotations.

MicrocephalyProminent noseHypotelorismPrimary amenorrheaAbnormal carpal morphologySeizureGlobal developmental delayHip dysplasiaObesitySubglottic stenosisDelayed skeletal maturationMadelung deformityClinodactyly of the 5th fingerShort middle phalanx of the 5th fingerShort statureLumbar scoliosisMicrotiaSevere intrauterine growth retardationSevere postnatal growth retardationLimb undergrowthSevere intellectual disabilityBilateral breast hypoplasia

Classification & Codes

Orphanet Code

ORPHA:319675
Seckel syndrome 7
OrphanetORPHA:319675
Treatments0 drug(s)
Symptoms on record22 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO