serotonin syndrome

MeSH: D020230ORPHA: 43116

Overview

symptoms caused by an excess of serotonin in the central nervous system

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with serotonin syndrome, sourced from HPO and Orphanet clinical annotations.

Abnormality of the autonomic nervous systemRestlessnessIrritabilityAnxietyMental deteriorationConfusionMyoclonusTremorTachycardiaDiarrheaNauseaInsomniaAbnormal saccadic eye movementsAgitationHypertensionHyperhidrosisSeizureHyperreflexiaClonusTachypneaLactic acidosisMydriasisDecreased vigilanceHallucinationsComaHypertoniaHepatic failureAcute kidney injuryFeverRigidityHypotensionRhabdomyolysisDisseminated intravascular coagulationDelirium

Classification & Codes

MeSH Code

D020230

Orphanet Code

ORPHA:43116
serotonin syndrome
MeSHD020230
OrphanetORPHA:43116
Treatments0 drug(s)
Symptoms on record34 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO