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severe hemophilia A

ORPHA: 169802

Contents

  1. 1. Available Treatments
  2. 2. Clinical Presentation
  3. 3. Classification & Codes

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with severe hemophilia A, sourced from HPO and Orphanet clinical annotations.

Reduced factor VIII activityProlonged partial thromboplastin timeEpistaxisBruising susceptibilityPoor wound healingJoint swellingPersistent bleeding after traumaProlonged bleeding after surgeryJoint hemorrhageOral cavity bleedingMenorrhagiaLimitation of joint mobilityAnemiaIntracranial hemorrhageGastrointestinal hemorrhageHeadacheArthralgiaLimb joint contractureProgressive joint destructionReduced von Willebrand factor activityIntramuscular hematomaCephalohematomaMacroscopic hematuriaProlonged bleeding following circumcisionSubdural hemorrhageEpidural hemorrhageSynovitis

Classification & Codes

Orphanet Code

ORPHA:169802
severe hemophilia A
OrphanetORPHA:169802
Treatments0 drug(s)
Symptoms on record27 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO