Severe X-linked intellectual disability, Gustavson type

MeSH: C536759ORPHA: 3078

Overview

medical condition

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Severe X-linked intellectual disability, Gustavson type, sourced from HPO and Orphanet clinical annotations.

MicrocephalyOptic atrophySeizureHypertoniaSevere postnatal growth retardationProfound hearing impairmentBlindnessSpasticitySmall for gestational ageDilated fourth ventricleRecurrent upper respiratory tract infectionsSmall fontanelleApneic episodes in infancySevere intellectual disabilityBrain atrophyNasogastric tube feedingVesicoureteral refluxLarge fontanellesMicrognathiaAbnormal pinna morphologyMacrotiaTriphalangeal thumbDandy-Walker malformationCerebellar hypoplasiaMyoclonusCongenital hip dislocationVentricular septal defectRocker bottom footCalcaneovalgus deformityShort noseContractures of the large jointsSevere muscular hypotoniaLateral ventricle dilatationEquinovarus deformity

Classification & Codes

MeSH Code

C536759

Orphanet Code

ORPHA:3078
Severe X-linked intellectual disability, Gustavson type
MeSHC536759
OrphanetORPHA:3078
Treatments0 drug(s)
Symptoms on record34 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO