sialuria

ICD-10: E77.8MeSH: D029461ORPHA: 3166

Overview

lysosomal storage disease characterized by increased sialic acid in the urine

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with sialuria, sourced from HPO and Orphanet clinical annotations.

Thin upper lip vermilionCoarse facial featuresEpicanthusHypertelorismSmooth philtrumLow-set earsWide nasal bridgePeriorbital fullnessDysostosis multiplexCholelithiasisSeizureMild intellectual disabilityGeneralized hypotoniaJoint hypermobilityHepatosplenomegalyHoarse voiceLong halluxAbnormality of metabolism/homeostasisAbnormal facial shapeHepatomegalyMemory impairmentExpressive language delayHyperkinetic movementsEpisodic abdominal painHigh, narrow palateUpper airway obstructionElevated circulating hepatic transaminase concentrationProlonged partial thromboplastin time2-3 toe syndactylyAttention deficit hyperactivity disorderProlonged prothrombin timeNeuropathic spinal arthropathySleep apneaProminent foreheadAbnormality of the mitochondrionGlobal developmental delay

Classification & Codes

ICD-10 Code

E77.8

MeSH Code

D029461

Orphanet Code

ORPHA:3166
sialuria
ICD-10E77.8
MeSHD029461
OrphanetORPHA:3166
Treatments0 drug(s)
Symptoms on record36 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO