Snyder-Robinson syndrome

MeSH: C536678ORPHA: 3063

Overview

Human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Snyder-Robinson syndrome, sourced from HPO and Orphanet clinical annotations.

KyphoscoliosisCleft palateThick lower lip vermilionNarrow faceLong faceFacial asymmetryOsteoporosisArachnodactylyDisproportionate tall statureHypernasal speechUnsteady gaitKyphosisDecreased muscle massFloppy infantLong toeSlender toeCryptorchidismTesticular atrophyHypospadiasNarrow mouthHigh palateHypertelorismSmooth philtrumLow-set earsBulbous noseProminent nasal bridgeAnteverted naresWebbed neckUpslanted palpebral fissureSynophrysDental crowdingDelayed speech and language developmentMild intellectual disabilityMyoclonusAbsent speechAbnormal facial shapeGeneralized myoclonic seizureEEG abnormalityInability to walkRecurrent fracturesDifficulty standingInvoluntary movementsPatchy hypo- and hyperpigmentationUnilateral ptosisAsymmetry of the earsFocal motor seizureSparse eyebrowEctopic kidneyEverted lower lip vermilionBrachycephalyMandibular prognathiaShort philtrumCupped earSmall earlobeThickened helicesProptosisPectus excavatumPectus carinatumMegalencephalyCerebral edemaProfound intellectual disabilityShort statureWide intermamillary distanceAbnormality of the Leydig cellsHigh myopiaCamptodactyly

Classification & Codes

MeSH Code

C536678

Orphanet Code

ORPHA:3063
Snyder-Robinson syndrome
MeSHC536678
OrphanetORPHA:3063
Treatments0 drug(s)
Symptoms on record66 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO