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spastic paraparesis-deafness syndrome

MeSH: C536692ORPHA: 2815

Contents

  1. 1. Overview
  2. 2. Available Treatments
  3. 3. Clinical Presentation
  4. 4. Classification & Codes

Overview

Spastic paraparesis-deafness syndrome is a chronic neurodegenerative disorder characterised by spastic paraparesis (beginning at about 10 years of age) and hearing deficits

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with spastic paraparesis-deafness syndrome, sourced from HPO and Orphanet clinical annotations.

HypogonadismSensorineural hearing impairmentVisual impairmentCataractNystagmusAtaxiaGait disturbanceHyperreflexiaSpastic paraparesisShort statureHemiplegia/hemiparesisImpaired pain sensationAbnormality of movement

Classification & Codes

MeSH Code

C536692

Orphanet Code

ORPHA:2815
spastic paraparesis-deafness syndrome
MeSHC536692
OrphanetORPHA:2815
Treatments0 drug(s)
Symptoms on record13 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO