spinocerebellar ataxia type 18

MeSH: C537197ORPHA: 98771

Overview

Spinocerebellar ataxia type 18 (SCA18) is a very rare subtype of type I autosomal dominant cerebellar ataxia (ADCA type I; see this term). It is characterized by sensory neuropathy and cerebellar ataxia.

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with spinocerebellar ataxia type 18, sourced from HPO and Orphanet clinical annotations.

AreflexiaMuscle weaknessGait ataxiaSomatic sensory dysfunctionHearing impairmentDysarthriaDysmetriaPes cavusLower limb hyperreflexiaHyporeflexia of lower limbsSensorimotor neuropathyMuscle fibrillationNystagmusCerebellar atrophyHead tremorSkeletal muscle atrophyPeripheral axonal neuropathyTitubation

Classification & Codes

MeSH Code

C537197

Orphanet Code

ORPHA:98771
spinocerebellar ataxia type 18
MeSHC537197
OrphanetORPHA:98771
Treatments0 drug(s)
Symptoms on record18 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO