spinocerebellar ataxia type 2
ORPHA: 98756
Overview
Spinocerebellar ataxia type 2 (SCA2) is a subtype of type I autosomal dominant cerebellar ataxia (ADCA type I; see this term) characterized by truncal ataxia, dysarthria, slowed saccades and less commonly ophthalmoparesis and chorea
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with spinocerebellar ataxia type 2, sourced from HPO and Orphanet clinical annotations.
Progressive cerebellar ataxiaAbnormal substantia nigra morphologySlow saccadic eye movementsSupranuclear ophthalmoplegiaNystagmusDementiaDysarthriaHyporeflexiaGeneralized hypotoniaDystoniaGait ataxiaChoreaPostural tremorFasciculationsAbnormal spinocerebellar tract morphologyMuscle spasmOlivopontocerebellar hypoplasiaSpinal cord dorsal column hypomyelinationCerebellar Purkinje layer atrophyAbnormal cell morphologyKinetic tremorOphthalmoparesisParkinsonismCerebral cortical atrophyAbnormal cortical gyrationHyperactive deep tendon reflexesCerebral white matter atrophy
Classification & Codes
Orphanet Code
ORPHA:98756spinocerebellar ataxia type 2
| Orphanet | ORPHA:98756 |
| Treatments | 0 drug(s) |
| Symptoms on record | 27 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO