spinocerebellar ataxia type 27
MeSH: C537204ORPHA: 98764
Overview
Spinocerebellar ataxia type 27 (SCA27) is a very rare subtype of type I autosomal dominant cerebellar ataxia (ADCA type I; see this term). It is characterized by early-onset tremor, dyskinesia, and slowly progressive cerebellar ataxia.
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with spinocerebellar ataxia type 27, sourced from HPO and Orphanet clinical annotations.
Gait disturbanceGaze-evoked nystagmusDysarthriaTremorAggressive behaviorPes cavusGait ataxiaLimb ataxiaTruncal ataxiaMemory impairmentSensory axonal neuropathyStrabismusRed-green dyschromatopsiaDepressionMild intellectual disabilityCerebellar atrophyHand tremorAkinesiaDysgraphia
Classification & Codes
MeSH Code
C537204Orphanet Code
ORPHA:98764spinocerebellar ataxia type 27
| MeSH | C537204 |
| Orphanet | ORPHA:98764 |
| Treatments | 0 drug(s) |
| Symptoms on record | 19 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO