spinocerebellar ataxia type 42

ORPHA: 458803

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with spinocerebellar ataxia type 42, sourced from HPO and Orphanet clinical annotations.

DysarthriaAbnormal cerebellum morphologyUnsteady gaitNeurodevelopmental abnormalityUrinary urgencyDepressionSaccadic smooth pursuit interruptionsCerebellar atrophyDysphagiaSpastic gaitGait ataxiaBabinski signCerebellar vermis atrophyImpaired vibration sensation at anklesGaze-evoked horizontal nystagmusEyelid myokymiaUrinary incontinenceStrabismusHypometric saccadesNystagmusDiplopiaImpotenceVertigoResting tremorHead tremorAlzheimer diseaseScoliosisPsoriasiform dermatitisUpper limb postural tremorAtrophy/Degeneration affecting the brainstemReduced brain N-acetyl aspartate level by MRSHyperintensity of cerebral white matter on MRI

Classification & Codes

Orphanet Code

ORPHA:458803
spinocerebellar ataxia type 42
OrphanetORPHA:458803
Treatments0 drug(s)
Symptoms on record32 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO