spondyloepimetaphyseal dysplasia, aggrecan type

MeSH: C567558ORPHA: 171866

Overview

Spondyloepimetaphyseal dysplasia, aggrecan type is a new form of skeletal dysplasia characterized by severe short stature, facial dysmorphism and characteristic radiographic findings

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with spondyloepimetaphyseal dysplasia, aggrecan type, sourced from HPO and Orphanet clinical annotations.

Mandibular prognathiaPosteriorly rotated earsShort neckBrachydactylyJoint hypermobilityBarrel-shaped chestAbnormal nail morphologyLumbar hyperlordosisMesomeliaRelative macrocephalyAbsent nasal bridgeRhizomeliaBroad thumbMidface retrusionHoarse voiceAbnormal respiratory system physiology

Classification & Codes

MeSH Code

C567558

Orphanet Code

ORPHA:171866
spondyloepimetaphyseal dysplasia, aggrecan type
MeSHC567558
OrphanetORPHA:171866
Treatments0 drug(s)
Symptoms on record16 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO