STAR syndrome
MeSH: C567475ORPHA: 140952
Overview
This syndrome is characterised by the association of toe syndactyly, facial dysmorphism including telecanthus (abnormal distance between the eyes) and a broad nasal tip, urogenital malformations and anal atresia
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with STAR syndrome, sourced from HPO and Orphanet clinical annotations.
Lop earToe syndactylyAnal atresiaClinodactyly of the 5th fingerShort statureLabial hypoplasiaVesicoureteral refluxRenal insufficiencyHorseshoe kidneyEctopic kidneyRenal agenesisThin upper lip vermilionBulbous noseWide nasal bridgeTelecanthusBicornuate uterusAbnormal cardiac septum morphologyClitoral hypertrophyMyopiaRetinal dystrophyEyelid colobomaSeizureAortic regurgitationHypoplasia of the radiusSyringomyeliaPulmonary artery stenosisMacular dystrophyMitral atresia
Classification & Codes
MeSH Code
C567475Orphanet Code
ORPHA:140952STAR syndrome
| MeSH | C567475 |
| Orphanet | ORPHA:140952 |
| Treatments | 0 drug(s) |
| Symptoms on record | 28 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO