systemic lupus erythematosus
MeSH: D008180ORPHA: 536
Overview
inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with systemic lupus erythematosus, sourced from HPO and Orphanet clinical annotations.
Lupus nephritisAnti-ribosome Po antibody positivityAnti-complement component C1q antibody positivityDecreased circulating complement C4 concentrationAnti-titin antibody positivityOral ulcerProteinuriaWeight lossFeverAnorexiaAntinuclear antibody positivityFatigueMalaiseHematuriaHypertensionArthritisAlopeciaDecreased total leukocyte countAntineutrophil antibody positivityDecreased circulating complement C3 concentrationPolyarticular arthritisPyuriaMalar rashRaynaud phenomenonDepressionCutaneous photosensitivitySeizureThrombocytopeniaHemolytic anemiaLymphadenopathyDiscoid lupus rashAnti-dsDNA antibody positivityAnti-La/SS-B antibody positivityAnti-U1 ribonucleoprotein antibody positivityAnti-Sm antibody positivityAnti-nucleoporin 62 antibody positivityAnti-Ro52/TRIM21 antibody positivityAnti-phosphatidic acid antibody positivitySerositisAbnormal pigmentation of the oral mucosaAbnormality of salivationCheilitisRetinopathyChorea
Classification & Codes
MeSH Code
D008180Orphanet Code
ORPHA:536systemic lupus erythematosus
| MeSH | D008180 |
| Orphanet | ORPHA:536 |
| Treatments | 0 drug(s) |
| Symptoms on record | 44 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO