TAFRO syndrome

ORPHA: 457077

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with TAFRO syndrome, sourced from HPO and Orphanet clinical annotations.

HepatosplenomegalyThrombocytopeniaLymphadenopathyElevated circulating C-reactive protein concentrationAnasarcaRenal insufficiencyAscitesSplenomegalyAnemiaFeverIncreased total leukocyte countPleural effusionHepatomegalyElevated circulating alkaline phosphatase concentrationIncreased megakaryocyte countMyelofibrosisIncreased circulating interleukin 6 concentrationElevated vascular endothelial growth factor levelReduced circulating lactate dehydrogenase concentration

Classification & Codes

Orphanet Code

ORPHA:457077
TAFRO syndrome
OrphanetORPHA:457077
Treatments0 drug(s)
Symptoms on record19 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO