Tangier disease
MeSH: D013631ORPHA: 31150
Overview
extremely rare inherited human disorder
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with Tangier disease, sourced from HPO and Orphanet clinical annotations.
HypertriglyceridemiaHypocholesterolemiaEctropionDry skinHepatosplenomegalyAbdominal painDistal muscle weaknessChronic noninfectious lymphadenopathyPeripheral axonal neuropathyAccelerated atherosclerosisCoronary artery stenosisProgressive peripheral neuropathyNail dystrophyOrange discolored tonsilsFacial diplegiaLeft ventricular hypertrophyThrombocytopeniaAnemiaSyringomyeliaCorneal opacityCarotid artery stenosisImpaired temperature sensation
Classification & Codes
MeSH Code
D013631Orphanet Code
ORPHA:31150Tangier disease
| MeSH | D013631 |
| Orphanet | ORPHA:31150 |
| Treatments | 0 drug(s) |
| Symptoms on record | 22 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO