Tatton-Brown–Rahman syndrome
ORPHA: 404443
Overview
human disease
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with Tatton-Brown–Rahman syndrome, sourced from HPO and Orphanet clinical annotations.
MacrocephalyProportionate tall statureAtypical behaviorObesityModerate intellectual disabilityKyphoscoliosisFloppy infantCryptorchidismCoarse facial featuresRound faceThick eyebrowAnxietySeizureMild intellectual disabilityJoint hypermobilityWidely-spaced maxillary central incisorsAtrial septal defectShort toeVentriculomegalyChiari malformationDevelopmental regressionWidely spaced toesSevere intellectual disabilityNarrow palpebral fissureSchizophreniaMandibular prognathiaHypertelorismAggressive behaviorUmbilical herniaPatent ductus arteriosusMitral regurgitationShort columellaDeep philtrumAortic root aneurysmProportionate short statureTricuspid regurgitationBipolar affective disorderSupraventricular tachycardia with an accessory connection mediated pathwayMyeloid leukemiaNeuroendocrine neoplasm
Classification & Codes
Orphanet Code
ORPHA:404443Tatton-Brown–Rahman syndrome
| Orphanet | ORPHA:404443 |
| Treatments | 0 drug(s) |
| Symptoms on record | 40 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO