Temple-Baraitser syndrome

MeSH: C567516ORPHA: 420561

Overview

medical condition

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Temple-Baraitser syndrome, sourced from HPO and Orphanet clinical annotations.

Everted upper lip vermilionTented upper lip vermilionHypoplastic thumbnailAbsent nail of halluxWide mouthMicrocephalyCoarse facial featuresEpicanthusHypertelorismLong philtrumMacrotiaWide nasal bridgeWide noseLong eyelashesThick eyebrowDelayed eruption of teethSeizureGeneralized hypotoniaAbsent speechBilateral ptosisLong halluxConstipationMyopathic faciesEEG abnormalityShort statureDepressed nasal bridgeAplastic/hypoplastic toenailSevere intellectual disabilityBroad thumbSevere global developmental delayAbnormal brain morphologyThick vermilion borderOpen mouthGingival overgrowthHigh palateEverted lower lip vermilionMalar flatteningFull cheeksLow anterior hairlineAnteverted naresAbsent toenailHypoplastic fingernailDelayed phalangeal epiphyseal ossificationTriangular shaped distal phalanx of the thumbShort phalanx of the thumbShort distal phalanx of fingerHigh anterior hairlineThick nasal alae

Classification & Codes

MeSH Code

C567516

Orphanet Code

ORPHA:420561
Temple-Baraitser syndrome
MeSHC567516
OrphanetORPHA:420561
Treatments0 drug(s)
Symptoms on record48 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO