Thakker-Donnai syndrome

ORPHA: 1780

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Thakker-Donnai syndrome, sourced from HPO and Orphanet clinical annotations.

HydronephrosisRectovaginal fistulaNarrow mouthHypertelorismPosteriorly rotated earsMacrotiaBulbous noseAnteverted naresWebbed neckShort neckUpslanted palpebral fissureLong palpebral fissureCongenital diaphragmatic herniaHypotoniaAgenesis of corpus callosumCommunicating hydrocephalusIntrauterine growth retardationVentricular septal defectTetralogy of FallotTransposition of the great arteriesAnal atresiaTracheoesophageal fistulaDownturned corners of mouthHemivertebraeCervical C2/C3 vertebral fusion

Classification & Codes

Orphanet Code

ORPHA:1780
Thakker-Donnai syndrome
OrphanetORPHA:1780
Treatments0 drug(s)
Symptoms on record25 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO