Tietz syndrome

ICD-10: E70.3MeSH: C536919ORPHA: 42665

Overview

monogenic disease that is characterized by congenital profound bilateral sensorineural hearing loss and generalized albino-like hypopigmentation of skin, eyes and hair that has material basis in mutation in the MITF gene on chromosome 3p13

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Tietz syndrome, sourced from HPO and Orphanet clinical annotations.

Hearing impairmentAbnormal anterior chamber morphologyAbnormality of skin pigmentationHypopigmentation of the skinWhite eyebrowHypopigmentation of hair

Classification & Codes

ICD-10 Code

E70.3

MeSH Code

C536919

Orphanet Code

ORPHA:42665
Tietz syndrome
ICD-10E70.3
MeSHC536919
OrphanetORPHA:42665
Treatments0 drug(s)
Symptoms on record6 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO
Tietz syndrome | OrphanDrug