toxic epidermal necrolysis
ICD-10: L51.2ORPHA: 95455
Overview
Severe skin reaction
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with toxic epidermal necrolysis, sourced from HPO and Orphanet clinical annotations.
Elevated circulating hepatic transaminase concentrationMyalgiaRhinitisCoughAbnormal bronchus morphologyPharyngitisGenital blisteringAcantholysisSkin ulcerOral mucosal blistersOral-pharyngeal dysphagiaAbnormal penis morphologyXerostomiaKeratitisVisual lossPhotophobiaDepressionHematuriaHypopigmentation of the skinTrichiasisAbnormality of the larynxDecreased total neutrophil countAcute kidney injuryDiarrheaPneumoniaAbdominal distentionAbnormality of the anusGastrointestinal inflammationRespiratory failure requiring assisted ventilationNail dystrophyRenal tubular epithelial necrosisOral synechiaGeneralized abnormality of skinAnterior uveitisChemosisModerate albuminuriaVaginal strictureVulvodyniaVaginal drynessIncreased tear productionDysuriaCorneal erosionSymblepharonBlindnessAnonychiaChronic lung diseaseIntestinal perforationSepsisFeverAbnormal blistering of the skinInflammatory abnormality of the skinFatigueConjunctival hyperemiaConjunctivitisAbnormality of the pharynxAnxietyHyperpigmentation of the skinAtypical scarring of skinSkin rashKeratoconjunctivitis siccaAnemiaAnorexiaRespiratory distressHeadacheAllergic response
Classification & Codes
ICD-10 Code
L51.2Orphanet Code
ORPHA:95455toxic epidermal necrolysis
| ICD-10 | L51.2 |
| Orphanet | ORPHA:95455 |
| Treatments | 0 drug(s) |
| Symptoms on record | 65 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO