transgrediens et progrediens palmoplantar keratoderma
ORPHA: 495
Overview
human disease
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with transgrediens et progrediens palmoplantar keratoderma, sourced from HPO and Orphanet clinical annotations.
Diffuse palmoplantar hyperkeratosisHigh palateFacial erythemaThickened skinHyperconvex nailDystrophic toenailRecurrent bacterial skin infectionsNonepidermolytic palmoplantar hyperkeratosisPlantar hyperkeratosisDystrophic fingernailsPalmar hyperkeratosisRecurrent cutaneous fungal infectionsFlexion contracture of fingerAngular cheilitisOnychogryphosisAmniotic constriction ringErythematous plaqueLichenoid skin lesion
Classification & Codes
Orphanet Code
ORPHA:495transgrediens et progrediens palmoplantar keratoderma
| Orphanet | ORPHA:495 |
| Treatments | 0 drug(s) |
| Symptoms on record | 18 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO