tricho-hepato-enteric syndrome

ORPHA: 84064

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with tricho-hepato-enteric syndrome, sourced from HPO and Orphanet clinical annotations.

Abnormal facial shapeIntractable diarrheaWoolly hairImmunodeficiencyHypertelorismBroad foreheadWide nasal bridgeMild intellectual disabilityGlobal developmental delayAbnormality of the liverCirrhosisHepatic fibrosisIntrauterine growth retardationSmall for gestational ageHepatomegalyBrittle hairPanhypogammaglobulinemiaShort statureHypopigmentation of hairTrichorrhexis nodosaAbnormal skin morphologyProminent foreheadVillous atrophyDependency on intravenous nutritionUncombable hairCafe-au-lait spotDry skinAbnormal heart morphologyDecreased total lymphocyte countThrombocytosisColitisRecurrent infectionsGastritisAbnormality of iron homeostasisIncreased mean platelet volumeInguinal herniaRenal hypoplasiaPolycystic kidney dysplasiaGlaucomaHypoplasia of the thymusHypothyroidismVentricular septal defectAtrial septal defectTetralogy of FallotPatent ductus arteriosusBicuspid aortic valveAortic regurgitationSplenomegalyHepatoblastomaPeripheral pulmonary artery stenosisGeneralized hypopigmentationBloody diarrhea

Classification & Codes

Orphanet Code

ORPHA:84064
tricho-hepato-enteric syndrome
OrphanetORPHA:84064
Treatments0 drug(s)
Symptoms on record52 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO