triploid syndrome
MeSH: D057885ORPHA: 3376
Overview
extremely rare chromosomal disorder occuring during human embryogenesis, causing severe abnormalities in fetal development and usually lethal in the prenatal stage
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with triploid syndrome, sourced from HPO and Orphanet clinical annotations.
Posteriorly rotated earsIntrauterine growth retardationAbnormality of chromosome segregationDecreased skull ossificationHypoplasia of penisMacroglossiaCleft palateMicrognathiaCataractIris colobomaNarrow chestOmphalocelePolyhydramniosHepatomegalyFinger syndactylyAplasia/Hypoplasia affecting the eyeNon-midline cleft of the upper lipAmbiguous genitaliaNarrow mouthHydrocephalusMacrocephalyShort neckHoloprosencephalyAbnormal cardiac septum morphologyAbnormality of the pancreasMeningoceleIntestinal malrotationAbnormality of the gallbladderAplasia/Hypoplasia of the corpus callosumCryptorchidismHypospadiasWide mouthAbnormal cranial suture/fontanelle morphologyHypertelorism
Classification & Codes
MeSH Code
D057885Orphanet Code
ORPHA:3376triploid syndrome
| MeSH | D057885 |
| Orphanet | ORPHA:3376 |
| Treatments | 0 drug(s) |
| Symptoms on record | 34 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO