trisomy 18p

MeSH: C538307ORPHA: 1715

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with trisomy 18p, sourced from HPO and Orphanet clinical annotations.

Thin vermilion borderSloping foreheadAbnormal pinna morphologyPreauricular skin tagUnderdeveloped nasal alaeWide nasal bridgeTelecanthusBlepharophimosisUpslanted palpebral fissureHypotelorismMild intellectual disabilityPyloric stenosisHighly arched eyebrowPolyphagiaAttention deficit hyperactivity disorderBilateral cryptorchidismMidface retrusionNarrow mouthAbnormal finger morphologyAbnormal foot morphologyMicrocephalyMicrognathiaNeonatal hypotoniaIntrauterine growth retardationHigh, narrow palateShort statureFacial palsyAbnormal cardiovascular system morphology

Classification & Codes

MeSH Code

C538307

Orphanet Code

ORPHA:1715
trisomy 18p
MeSHC538307
OrphanetORPHA:1715
Treatments0 drug(s)
Symptoms on record28 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO