trisomy 20p

MeSH: C535371ORPHA: 261318

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with trisomy 20p, sourced from HPO and Orphanet clinical annotations.

Full cheeksRound faceProtruding earShort neckThick eyebrowHypotoniaGait disturbanceJoint hypermobilityAbnormal facial shapeAbnormal speech patternIncoordinationHighly arched eyebrowAbnormality of chromosome segregationAbnormal form of the vertebral bodiesAbnormal autonomic nervous system physiologyCognitive impairmentHerniaInguinal herniaAbnormality of the dentitionAbnormal palate morphologyBrachycephalyEpicanthusLow anterior hairlineHypertelorismMicrognathiaPosteriorly rotated earsMacrotiaAnteverted naresStrabismusUpslanted palpebral fissureBrachydactylyPlagiocephalyUmbilical herniaAbnormal foot morphologyTalipesLow posterior hairlineCoarse hairSpina bifidaShort noseAbnormal hip bone morphologyFinger syndactylyThick hairCryptorchidismHypospadiasMacroorchidismAbnormality of the ureterAbnormality of the kidneyHydronephrosisEverted lower lip vermilionThin vermilion borderDolichocephalySmooth philtrumShort philtrumDownslanted palpebral fissuresBlepharophimosisMicrodontiaPlatyspondylyPreaxial hand polydactylyFrontal bossingScoliosisDownturned corners of mouthKyphosisVertebral segmentation defectReduced bone mineral densityEctopic anusMultiple renal cystsWide intermamillary distanceAbnormal antihelix morphologyAbnormal cardiovascular system morphologyCamptodactyly of fingerAbnormal localization of kidney

Classification & Codes

MeSH Code

C535371

Orphanet Code

ORPHA:261318
trisomy 20p
MeSHC535371
OrphanetORPHA:261318
Treatments0 drug(s)
Symptoms on record71 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO