VACTERL association
MeSH: C536495ORPHA: 887
Overview
syndrome that is characterized by the presence of at least three of the following: vertebral defects, anal atresia, cardiac defects, tracheo-esophageal fistula, renal anomalies, and limb abnormalities
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with VACTERL association, sourced from HPO and Orphanet clinical annotations.
PolyhydramniosPremature birthAnal atresiaTracheal stenosisAplasia/Hypoplasia of the lungsEctopic kidneyRenal agenesisCongenital diaphragmatic herniaLaryngomalaciaAbnormal cardiac septum morphologyTracheoesophageal fistulaVertebral segmentation defectAplasia/Hypoplasia of the radiusAbnormal cardiovascular system morphologyMulticystic kidney dysplasiaAbnormal morphology of female internal genitaliaCryptorchidismHypospadiasBifid scrotumAmbiguous genitaliaHydronephrosisCleft palateLarge fontanellesAbnormal rib morphologyAbnormality of the urethraCavernous hemangiomaPreaxial hand polydactylySingle umbilical arteryIntrauterine growth retardationOmphaloceleAbnormality of the pancreasOccipital encephaloceleAnencephalyAbnormal sacrum morphologyAbnormal intervertebral disk morphologyAbnormality of the gallbladderFinger syndactylyHypoplasia of penisAnorectal anomalyNon-midline cleft of the upper lipPosteriorly rotated ears
Classification & Codes
MeSH Code
C536495Orphanet Code
ORPHA:887VACTERL association
| MeSH | C536495 |
| Orphanet | ORPHA:887 |
| Treatments | 0 drug(s) |
| Symptoms on record | 41 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO