variant ABeta2M amyloidosis
ORPHA: 314652
Overview
#946;2M) leading to progressive gastrointestinal dysfunction, SjC6gren syndrome (see this term) and autonomic neuropathy
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with variant ABeta2M amyloidosis, sourced from HPO and Orphanet clinical annotations.
Renal amyloidosisConstrictive median neuropathyChronic kidney diseaseAbnormality of the tongueSpinal cord compressionPathologic fractureArthralgia of the hipGastrointestinal infarctionsSensorimotor neuropathyAbnormal salivary gland morphologyAbnormal skeletal muscle morphologyCardiovascular calcificationMultiple bony cystic lesionsHepatic amyloidosisCutaneous amyloidosisAbnormal autonomic nervous system physiologyReduced left ventricular ejection fractionAbnormal vascular morphologyShoulder painWrist painKnee painCardiac amyloidosisIntestinal perforationAmyloidosis of peripheral nerves
Classification & Codes
Orphanet Code
ORPHA:314652variant ABeta2M amyloidosis
| Orphanet | ORPHA:314652 |
| Treatments | 0 drug(s) |
| Symptoms on record | 24 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO