Waardenburg's syndrome

MeSH: D014849ORPHA: 3440

Overview

genetic condition involving hearing loss and depigmentation

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Waardenburg's syndrome, sourced from HPO and Orphanet clinical annotations.

Hearing impairmentProminent nasal bridgeSynophrysAbnormality of skin pigmentationHypopigmented skin patchesHeterochromia iridisAbnormal facial shapePremature graying of hairHypopigmentation of hairSensorineural hearing impairmentUnderdeveloped nasal alaeWide nasal bridgeAbnormality of the eyeTelecanthusAbnormal eyebrow morphologyWhite forelockCongenital sensorineural hearing impairmentOrofacial cleftPtosisBlue iridesWhite eyelashesAganglionic megacolonVertigoSpina bifidaMyelomeningoceleIntestinal obstructionVestibular areflexiaPeripheral neuropathyAbnormality of the gastrointestinal tractCamptodactylyElbow contractureAplasia/Hypoplasia of the colon

Classification & Codes

MeSH Code

D014849

Orphanet Code

ORPHA:3440
Waardenburg's syndrome
MeSHD014849
OrphanetORPHA:3440
Treatments0 drug(s)
Symptoms on record32 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO