Wiedemann-Steiner syndrome

ORPHA: 319182

Overview

hereditary disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Wiedemann-Steiner syndrome, sourced from HPO and Orphanet clinical annotations.

Delayed speech and language developmentThin upper lip vermilionRound faceHypertelorismFacial asymmetryLong philtrumWide nasal bridgeLong eyelashesThick eyebrowAtypical behaviorAggressive behaviorMotor stereotypyShort attention spanAnxietyLow frustration toleranceHyperactivityDecreased response to growth hormone stimulation testTapered fingerHypotoniaDysphagiaDelayed gross motor developmentDelayed skeletal maturationCongenital, generalized hypertrichosisAccelerated skeletal maturationPostnatal growth retardationAbnormality of the elbowFeeding difficultiesShort palpebral fissureHigh palateMicrocephalyDolichocephalyEpicanthusHigh foreheadLow-set earsWebbed neckTelecanthusPtosisSynophrysPectus excavatumSacral dimpleAbnormality of the handIntellectual disabilitySeizureAbnormal corpus callosum morphologyFailure to thriveIntrauterine growth retardationGastroesophageal refluxGeneralized hirsutismPsychomotor deteriorationShort noseClinodactyly of the 5th fingerShort statureAplasia/Hypoplasia of the ribsRhizomeliaHyperextensibility at elbowFlat faceClinodactylyDilatation of renal calices

Classification & Codes

Orphanet Code

ORPHA:319182
Wiedemann-Steiner syndrome
OrphanetORPHA:319182
Treatments0 drug(s)
Symptoms on record58 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO