Wolfram-like syndrome

ORPHA: 411590

Overview

medical condition

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Wolfram-like syndrome, sourced from HPO and Orphanet clinical annotations.

Optic atrophyPsychosisDepressionDementiaAutistic behaviorAnxietyDiabetes mellitusMale hypogonadismAbnormal pinna morphologyGlaucomaDelayed pubertyCentral diabetes insipidusGlucose intoleranceProgressive cerebellar ataxiaGastrointestinal dysmotilityPeripheral axonal neuropathyPrimary gonadal insufficiencyCongenital sensorineural hearing impairmentAbnormality of the upper urinary tractHypothyroidismRespiratory insufficiencySevere postnatal growth retardation

Classification & Codes

Orphanet Code

ORPHA:411590
Wolfram-like syndrome
OrphanetORPHA:411590
Treatments0 drug(s)
Symptoms on record22 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO
Wolfram-like syndrome | OrphanDrug