Worster-Drought syndrome

MeSH: C536747ORPHA: 3465

Overview

Worster-Drought syndrome (WDS) is a form of cerebral palsy characterized by congenital pseudobulbar (suprabulbar) paresis manifesting as selective weakness of the lips, tongue and soft palate, dysphagia, dysphonia, drooling and jaw jerking

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Worster-Drought syndrome, sourced from HPO and Orphanet clinical annotations.

Abnormal cranial nerve morphologyAbnormal speech patternTongue muscle weaknessSpecific learning disabilityHyperreflexiaDysphoniaDysphagiaGastroesophageal refluxRecurrent respiratory infectionsDroolingTetraplegiaJaw hyperreflexiaGlue earCognitive impairmentMicrocephalySensorineural hearing impairmentSeizureAttention deficit hyperactivity disorder

Classification & Codes

MeSH Code

C536747

Orphanet Code

ORPHA:3465
Worster-Drought syndrome
MeSHC536747
OrphanetORPHA:3465
Treatments0 drug(s)
Symptoms on record18 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO