X-linked cerebral-cerebellar-coloboma syndrome syndrome

ORPHA: 163961

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with X-linked cerebral-cerebellar-coloboma syndrome syndrome, sourced from HPO and Orphanet clinical annotations.

HydrocephalusLow-set earsChorioretinal colobomaIntellectual disabilitySeizureGlobal developmental delayCerebellar vermis hypoplasiaVentriculomegalyAbnormal brainstem morphologyAbnormal cerebral cortex morphologyEpisodic tachypneaApneic episodes in infancyFloppy infantFeeding difficultiesNasogastric tube feedingRetrognathiaHypertelorismMicrognathiaPosteriorly rotated earsAreflexiaDandy-Walker malformationFrontal bossingDysphagiaPoor suckMeckel diverticulumAgenesis of cerebellar vermisShort noseSupernumerary ribsUncontrolled eye movementsUndetectable visual evoked potentialsThick nasal alae

Classification & Codes

Orphanet Code

ORPHA:163961
X-linked cerebral-cerebellar-coloboma syndrome syndrome
OrphanetORPHA:163961
Treatments0 drug(s)
Symptoms on record31 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO