X-linked ichthyosis
MeSH: D016114ORPHA: 461
Overview
skin condition caused by the hereditary deficiency of the steroid sulfatase (STS) enzyme that affects 1 in 2000 to 1 in 6000 males
Available Treatments (0)
No treatments linked yet
Clinical trials or compassionate use may be available — consult a specialist.
Clinical Presentation
Signs and symptoms associated with X-linked ichthyosis, sourced from HPO and Orphanet clinical annotations.
Dry skinHyperkeratosisHypohidrosisIchthyosisAttention deficit hyperactivity disorderOpacification of the corneal stromaCryptorchidismAutismMotor delayAbnormal speech patternDesquamation of skin soon after birthIntellectual disability
Classification & Codes
MeSH Code
D016114Orphanet Code
ORPHA:461X-linked ichthyosis
| MeSH | D016114 |
| Orphanet | ORPHA:461 |
| Treatments | 0 drug(s) |
| Symptoms on record | 12 signs |
| Status | published |
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO