X-linked mandibulofacial dysostosis

MeSH: C537102ORPHA: 1131

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with X-linked mandibulofacial dysostosis, sourced from HPO and Orphanet clinical annotations.

Posteriorly rotated earsHigh palateMicrocephalyTriangular faceMicrognathiaConductive hearing impairmentSensorineural hearing impairmentProtruding earProminent nasal bridgeWebbed neckDownslanted palpebral fissuresShort statureBranchial anomalyHypoplasia of the zygomatic boneCryptorchidismEpicanthusAplasia/Hypoplasia of the eyebrowFacial asymmetryPtosisPectus excavatumAbnormal mitral valve morphologyPulmonic stenosisAbnormality of the pulmonary arteryAsymmetric growth

Classification & Codes

MeSH Code

C537102

Orphanet Code

ORPHA:1131
X-linked mandibulofacial dysostosis
MeSHC537102
OrphanetORPHA:1131
Treatments0 drug(s)
Symptoms on record24 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO