Zimmermann-Laband syndrome 1

ORPHA: 3473

Overview

human disease

Available Treatments (0)

No treatments linked yet

Clinical trials or compassionate use may be available — consult a specialist.

Clinical Presentation

Signs and symptoms associated with Zimmermann-Laband syndrome 1, sourced from HPO and Orphanet clinical annotations.

Gingival fibromatosisWide mouthBulbous noseWide noseIntellectual disabilityJoint hypermobilityHypoplastic fingernailAbsent fingernailLarge fleshy earsGeneralized hypertrichosisAnterior open-bite malocclusionThickened earsMacroglossiaCleft palateBifid uvulaHigh palateHypertelorismMicrognathiaShort neckDownslanted palpebral fissuresTelecanthusCataractLong eyelashesThick eyebrowHypodontiaAbnormal external genitalia morphologySoft skinSeizureGrowth delaySplenomegalyPes cavusPes planusHallux valgusFacial hypertrichosisHepatomegalyFloppy infantSupernumerary toothAbnormal cardiovascular system morphologySensorineural hearing impairmentDeep plantar creasesDeep palmar creaseOvertubulated long bonesGeneralized hyperpigmentation

Classification & Codes

Orphanet Code

ORPHA:3473
Zimmermann-Laband syndrome 1
OrphanetORPHA:3473
Treatments0 drug(s)
Symptoms on record43 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO