Busulfan

Orphan DrugFDA Approved

Description

Busulfan is an alkylating agent used as a conditioning regimen prior to hematopoietic stem cell transplantation. It is commonly employed in the treatment of severe combined immunodeficiency disorders requiring bone marrow transplantation. The drug works by destroying bone marrow cells to prepare the patient for transplant.

Indications & Therapeutic Use

Conditioning treatment prior to allogeneic hematopoietic progenitor cell transplantation for chronic myelogenous leukemia, severe combined immunodeficiency

Global Availability (5 countries)

CountryAccess RouteRegulatory PathwayLead TimeStatus

Available Through

This drug is available for procurement through the following fulfilment partner.

Fulfilment Partner
Busulfan
Generic NameBusulfan
Brands1 brand available
Active IngredientBusulfan
Drug ClassConditioning treatment prior to allogeneic hematopoietic progenitor cell transplantation for chronic myelogenous leukemia
ManufacturerOtsuka Pharmaceutical
Dosage FormsIV infusion, 6mg/mL; Oral tablet, 2mg
Medical CodeL01AB01
Orphan StatusYes — Orphan Drug
Cold ChainNot Required
Lead Time14 days
Reg. StatusFDA Approved
Clinical TrialNCT00000000
Countries5 countries
Authority Signals
Last Verified3/21/2026
Data ConfidenceHigh (AI + Pharmacist)
Source Citations6 Validated Nodes